Bibliografía

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Bosch, L. J. W. et al. Novel Stool-Based Protein Biomarkers for Improved Colorectal Cancer Screening: A Case-Control Study. Ann Intern Med 167, 855–866 (2017).
Guo, T. et al. Rapid mass spectrometric conversion of tissue biopsy samples into permanent quantitative digital proteome maps. Nat Med 21, 407–413 (2015).
Nuciforo, P. et al. High HER2 protein levels correlate with increased survival in breast cancer patients treated with anti-HER2 therapy. Mol Oncol 10, 138–147 (2016).
Li, X.-J. et al. A blood-based proteomic classifier for the molecular characterization of pulmonary nodules. Science Translational Medicine 5, 207ra142–207ra142 (2013).
Silvestri, G. A. et al. Assessment of Plasma Proteomics Biomarker’s Ability to Distinguish Benign From Malignant Lung Nodules: Results of the PANOPTIC (Pulmonary Nodule Plasma Proteomic Classifier) Trial. Chest 154, 491–500 (2018).
Yi, L. et al. Targeted Quantification of Phosphorylation Dynamics in the Context of EGFR-MAPK Pathway. Anal. Chem. 90, 5256–5263 (2018).
Seeley, E. H. & Caprioli, R. M. MALDI imaging mass spectrometry of human tissue: method challenges and clinical perspectives. Trends Biotechnol 29, 136–143 (2011).
Schöne, C., Höfler, H. & Walch, A. MALDI imaging mass spectrometry in cancer research: combining proteomic profiling and histological evaluation. Clin. Biochem. 46, 539–545 (2013).
Steurer, S. et al. MALDI imaging-based identification of prognostically relevant signals in bladder cancer using large-scale tissue microarrays. Urol. Oncol. 32, 1225–1233 (2014).
Aebersold, R. et al. How many human proteoforms are there? Nat Chem Biol 14, 206–214 (2018).
Ntai, I. et al. Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk. Proc. Natl. Acad. Sci. U.S.A. 115, 4140–4145 (2018).
Savaryn, J. P., Catherman, A. D., Thomas, P. M., Abecassis, M. M. & Kelleher, N. L. The emergence of top-down proteomics in clinical research. Genome Med 5, 53 (2013).